The Buffalo Bills will host the Tennessee Titans at Highmark Stadium in Week 7.

The Bills (4-2) are coming off a crucial divisional win over the New York Jets in Week 6 and lead the AFC East. The Titans (1-4) stand toward the bottom of the AFC under first-year head coach Brian Callahan.

The Bills have an enticing new weapon on offense after trading for Amari Cooper from the Cleveland Browns. Even before Cooper’s arrival, the Bills rank third in the NFL in offensive DVOA through six weeks.

On the other hand, the Titans have been a disaster on offense. They are turning the ball over and they have struggled to pass consistently. The Titans do, however, boast the league’s top defense in yards allowed per game.

The Bills are favored by 9.5 points on Sunday but every week is a challenge in the NFL. They’ll need to execute the game plan to gain their fifth win of the year.

Here are three keys to a Bills win in Week 7:

Win the turnover battle

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When it comes to turning the ball over in 2024, the Bills and the Titans are at opposite ends of the spectrum. The Bills are ranked second in the NFL with a turnover differential of +8, while the Titans are ranked second-to-last with a turnover differential of -7. Will Levis leads the NFL in interceptions with seven. On the flip side, Buffalo’s Josh Allen has not thrown one.

The Bills need to do what they have been for much of the season, and that is win the turnover battle. The Bills are favored by nearly double digits in this one, but a couple of turnovers could shift the momentum quickly.

Get the receivers involved

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It’s not just newcomer Amari Cooper that has to get going in the Bills offense, it’s many of the other wide receivers who are still new to Allen. Among the WRs, only Khalil Shakir had played a game with Allen before the year. And it has shown through six weeks. Shakir has been the only consistent receiver (when healthy). He leads the Bills in receiving while ranking just 55th in the NFL in receiving yards.

The Titans have a stingy defense, but they haven’t seen an offense like the Bills’ this year, especially on the road. If the Bills can get Cooper going, it should open up opportunities for others. Perhaps Cooper is the missing ingredient that will have everybody eating again.

Limit the run

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It’s no secret that the Titans’ passing game has struggled this year, but one constant for them has been the play of running back Tony Pollard. He’s coming off games of 88 and 93 rushing yards, respectively. He’s averaging over four yards per carry and is 18th in the NFL in rushing yards despite already having a bye week. The team will be without RB Tyjae Spears due to injury, so it should be the Pollard show.

If the Bills can limit the Titans’ ground game, it should force Levis into uncomfortable third-and-longs. The idea of playing against a young QB who is turnover prone should have Bobby Babich’s defense foaming at the mouth.