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Week 11 is nearly a wrap, and betting lines are now available for Week 12. Here are our favorite early spread picks for the slate.

Seattle Seahawks (-12.5) vs. Tennessee Titans [Total: 41.5]

Best Bet: Seahawks -12.5

Despite four interceptions from Sam Darnold, in addition to a loss, the Seahawks managed to cover a three-point spread on the road against the Rams in Week 11, underscoring their status as the most profitable team in the NFL (80% cover rate). That win retains their unblemished road record against the spread (5-0), and now their road trip continues into Tennessee.

The Seahawks travel well (9.4-point average victory margin on the road) and have decimated lesser competition (13.3-point average victory margin as the favorite). Although this will be the most points they’ve had to lay this season, this line is very likely to move toward them as the week goes on, given the severity of the Titans’ limitations.  

Tennessee’s -13.0-point average game margin is the worst in the NFL by far, with the Bengals‘ -10.6 average margin ranking second worst.. Offensively, the Titans’ EPA per play number not only ranks last in the NFL for this season, but it also ranks as the lowest by any team through Week 11 over the past decade.  

Lowest EPA/Play Offenses Through Week 11

Calvin Ridley — who suffered a broken fibula in Week 11 — is out for the remainder of the season, leaving rookie quarterback Cam Ward to orchestrate this offense without his highest-graded receiver. Meanwhile, the Seahawks‘ defense allows the third-lowest passing yards per attempt on average (6.25) and the second-lowest scoring drive rate (30.1%). The Titans will need their best performance to finish this game within 14 points. 

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Minnesota Vikings vs. Green Bay Packers (-6.5) [Total: 41.5]

Best Bet: Packers -6.5

The Vikings are coming off a disappointing home loss to the Bears in which their offense was unable to get anything going, averaging -0.2 EPA per play. And worse than the overall performance was the continued struggles of quarterback J.J. McCarthy, who threw for only 4.5 yards per attempt on his way to a mere 58.5 PFF overall grade. McCarthy has been unable to create out of structure this season, and against a tough Packers defense in Week 12, there is little reason to think that will change.

The Vikings‘ defense was solid in Week 11, limiting Caleb Williams‘ production via the blitz, but Packers quarterback Jordan Love has found a huge amount of success on such plays, with the third-highest EPA per play mark. Even without running back Josh Jacobs, who suffered a knee injury in Week 11, Green Bay’s rushing offense is able to produce with Emanuel Wilson.

The Packers are also healthier at wide receiver, so their passing offense should only continue to improve, particularly in a terrific spot against a struggling Vikings defense.