Baker Mayfield delivered early fourth-quarter heroics to lead the Buccaneers past the 49ers, 30-19, improving Tampa Bay to 5-1. Mayfield threw two touchdown passes and extended a key drive with a spectacular third-and-14 scramble, setting up a 45-yard strike to rookie Tez Johnson for the clinching score. San Francisco, already banged up, lost star linebacker Fred Warner to a season-ending ankle injury, while Mac Jones threw for 347 yards but was picked off twice in the loss.