College Football Week 5: Line moves and totals swings to know

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Line moves tell a story — the edge comes from knowing whether it’s a true signal or just an overreaction. Injuries, weather and public pick releases are just a few of the forces that can push numbers around, but the real value comes from understanding which shifts actually matter.
Early in the season, markets are especially volatile as oddsmakers and bettors scramble for an accurate read on each team. Big swings are common, and while seeing that lines move is useful, identifying why they move is what creates opportunity to shape your stance and pinpoint the right entry points.
College football markets, in particular, are being bet into shape earlier than ever. What used to be a slow game of chicken, waiting for the best number at a decent limit, has become a sprint, with bettors and touts racing to grab value before limits peak later in the week.
Here, we’ll examine the notable market maker openers and how those numbers have shifted since Sunday.

Movement: Notre Dame -5 → -4
After opening in the spread dead zone, early money came in on Notre Dame, with most books moving the line to 6.5. A few shops briefly touched 7, and FanDuel even flashed a 7.5 before sharp money brought it back down. Since then, the action has swung toward Arkansas, with support for the trendy Week 5 home underdog pushing the line down to 4 and even 3.5 at several books.
The total has also moved significantly, climbing from an opener of 62 to as high as 65.5 before settling at 64.5 across the board.
Play: Over 64.5 (-105 at Novig, -110 elsewhere). Both defenses have had shaky starts to the season, and that trend looks likely to continue in what could be a high-scoring affair.
Indiana vs. Iowa
Movement: Indiana -4 → -8
Markets typically respond when you beat a top-10 team by 53 on the road — and that’s exactly what happened here. After opening at -4, Indiana was quickly bet up past the key number of 7, peaking at -9 on Monday afternoon. Since then, money has come back on Iowa, with the line now hovering between 7.5 and 8, depending on the book.
Both teams are coming off shootout wins, with combined scores of 73 and 66 in Week 4. However, this Week 5 Big Ten clash is expected to be decided in the trenches, with fewer fireworks anticipated.
Play: Iowa +8 (-113 at Rivers). Indiana looked dominant last week — no denying that. But this is a major swing from the lookahead line of 2.5 to 3. Iowa also notched a strong road win over previously unbeaten Rutgers. This feels more like an overreaction than a justified adjustment.
LSU vs. Ole Miss
Movement: LSU -1 → +1.5
While it hasn’t been a dramatic move, this matchup has seen a flip in favorites. The more notable shift occurred early Monday, when Ole Miss was bet up to a 3-point favorite — a number that quickly drew resistance and settled back to -1.5 across most books.
There’s still some quarterback uncertainty for the Rebels. Starter Austin Simmons is working through an injury, while backup Trinidad Chambliss has played well enough to make it a decision for Lane Kiffin.
Play: Ole Miss ML (-115 at MGM). Regardless of who starts at quarterback, this is a buy spot on Ole Miss. LSU is receiving too much credit for how good their early-season wins would have appeared in August.
Movement: Total 56.5 → 59.5
This total has climbed three points, reaching as high as 60.5 at some books. Of the eight combined games played by these teams this season, only one has gone under the total — Syracuse vs. UConn in Week 2. The move appears to have been driven largely by a public pick release.
Ohio State vs. Washington
Movement: Total 54.5 → 52
This total has seen some back-and-forth action, bouncing between 51.5 and 52.5 early in the week. Both numbers remain widely available at major books. The spread has also moved off the opener of 10, with Ohio State now sitting as an 8-point favorite at most shops — some even flashing 7.5.
The lack of explosiveness from Ohio State’s 2024 offense appears to be priced in. The market movement suggests skepticism that things will suddenly click in Week 5, particularly against a Washington defense that may be better equipped to contain them. The dip in both spread and total has shaved 3.25 points off Ohio State’s implied team total.