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Week 12 is here, and PFF’s analysts have locked in their favorite bets of the week, powered by the PFF Player Prop Tool.

The tool delivers real-time projections, matchup data, hit rates and the best available odds all in one place. It’s the same level of insight trusted by all 32 NFL teams, now at your fingertips.

These picks have gone 33-30-3 this season. Here are our analysts’ favorite bets for Week 12.

Trevor Sikkema (6-5)

QB Drake Maye, New England Patriots: Under 2.5 touchdown passes (-210 BetMGM)

Calling the under here has nothing to do with Maye’s ability or how well he’s playing. I just don’t expect him to be put in a situation where he needs to throw more than 2.5 touchdowns. The Patriots will likely look to control the game on the ground against a Cincinnati defense featuring the league’s lowest-graded linebacker group this season.

Dalton Wasserman (6-5)

QB Shedeur Sanders, Cleveland Browns: Over 158.5 passing yards (-114 Fanduel)

Sanders struggled in his regular-season debut last week, but he now faces a Las Vegas defense with the second-worst coverage grade in the league this season. His biggest issue against the Ravens last week was the blitz, and the Raiders blitz at the sixth-lowest rate in the NFL. They’ve also allowed at least 207 passing yards to all but one opposing starter this season. The Browns’ passing game has been abysmal, but this is a low bar Sanders should be able to clear.

Ben Linsey (9-2)

RB Kenneth Walker III, Seattle Seahawks: Anytime TD (+145 Fanatics)

The Seahawks have shown all season that they can put up points on inferior opponents, and they enter the week as nearly two-touchdown favorites against Tennessee. Since Seattle’s bye, Kenneth Walker has seen more carries than Zach Charbonnet inside the 10-yard line, and head coach Mike Macdonald said this week that Walker is “earning more opportunities to get the ball.”

In a matchup where Seattle projects to score often — and with the Titans unlikely to sustain long drives — this is a favorable price for Walker to find the end zone.

Mason Cameron (4-6-1)

QB Jared Goff, Detroit Lions: Under 31.5 pass attempts (-114 FanDuel)

Dan Campbell’s offense is built to set the tone on the ground, and this week brings a favorable matchup to do it against a Giants defense that struggles to defend the run. New York ranks 31st in both team run-defense grade (42.6) and EPA allowed per rush (0.173). The Lions already operate with the second-highest run-play rate in the NFL, and as more than two-score favorites, they should have ample opportunity to lean on the ground game as the focal point of their plan.

That likely leaves Jared Goff with little need to rack up passing volume.

Max Chadwick (4-6-1) 

WR Brian Thomas Jr., Jacksonville Jaguars: Under 4.5 receptions (+115 BetMGM)

Thomas has gone under this number in all but two games this season and hasn’t come close to matching the production he delivered as a rookie. His 18.9% drop rate in 2025 is the third-highest among qualified receivers, and he now faces a Cardinals defense that ranks 10th in team coverage grade. With Arizona holding the sixth-worst run-defense grade, this projects as a matchup where the Jaguars lean more on Travis Etienne Jr. than their passing game.

Gordon McGuinness (4-6-1) 

RB Chase Brown, Cincinnati Bengals: Under 59.5 rushing yards (-115 BetMGM)

Brown has gone over this total in three of his past four games, but the Patriots have been one of the league’s best run defenses this season, with no opposing running back clearing 60 rushing yards through the first 11 weeks. On top of New England’s defensive strength, the Patriots enter as seven-point favorites, making a negative game script likely for Cincinnati and reducing the chances of Brown handling consistent volume.