NFL Week 6: Line moves and totals swings to know

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In the most efficient betting market in sports, every move matters. NFL sides and totals attract massive liquidity, making them less volatile than their college football counterparts — but also more revealing. This article breaks down the key drivers of line movement and offers tools to help you distinguish overreactions from sharp, justified adjustments.
Injuries, weather, and public pick releases are just a few factors that can swing numbers. But spotting early signals—before prices settle into full efficiency—is where betting edges are made. Below, we’ll walk through how notable market-maker openers have shifted since Sunday and what those moves might be telling us.
Movement: Broncos -6.5 → -7
The Broncos opened as favorites and were quickly bet up to -7, with some shops touching -8 before settling at a consensus -7. A few books are still showing 7.5s and heavily juiced 6.5s. If the number gets closer to a flat 6.5, it could be a strong buy point for Denver in London.
Movement: Colts -5 → -7
The Colts have been steadily bet up to 7-point favorites, with some books briefly touching 7.5 — though not the primary market-makers. That said, 7.5s are still available but likely won’t last long.
Play: Arizona +7.5 (-120 at Rivers)
Capitalize on what appears to be an overreaction to a misleading final score last week. If not for Demercado’s late fumble at the goal line, this line likely wouldn’t have hit a touchdown.
Movement: Total 44.5 → 47.5
After both teams participated in shootouts last week, the total has steadily climbed to 47.5 — not due to a single catalyst, but rather consistent support over time. There’s been little resistance to the rise, though 48 has yet to appear across books. The current market is split between 47 and 47.5, with a slight lean toward the higher number.
Play: Under 47.5 (-110 at ost books)
Both teams faced opponents last week that tend to create inflated scoring environments, and that influence is helping shape this number. As a result, there’s some added value on the under here. I expect this total to settle closer to 47, if not slightly below, by kickoff.
Movement: Titans +6 → +4.5
Both teams enter Week 6 at 1–4. After opening at 6, a public pick release on Monday bumped the line down to 4.5. Tennessee’s first win last week over Arizona felt more reactionary than foundational, and this play feels more like fading Las Vegas than backing Tennessee. Add to that Pete Carroll’s comments about possibly benching Geno Smith in favor of Kenny Pickett—and you’ve got a matchup ripe for an early Titans edge against a vulnerable Raiders offensive line.
Movement: Total 50 → 53
The total has quietly climbed 3 points from the opener, reaching as high as 53.5 before some under money brought it back down. A few 52.5s are still available. Unlike recent years, this Chiefs offense is playing faster—ranking 7th in average play clock remaining—while Detroit continues to move the ball efficiently. That combination has helped make this Sunday Night Football clash the week’s highest projected total.