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WEEK 5 2025, Sunday, October 5th
Early Morning Game
Minnesota Vikings (2-2) T-3rd NFC North @ Cleveland Browns (1-3) T-3rd AFC North
- Location: Tottenham Hotspur Stadium, Tottenham, London, England
- Time: 9:30 AM EST
- TV: NFL Network
- Odds: Vikings -3.5; Over/Under 35.5 (via FanDuel sportsbook)
Late Afternoon Games
Tampa Bay Buccaneers (3-1) 1st NFC South @ Seattle Seahawks (3-1) 2nd NFC West
- Location: Lumen Field, Seattle, Washington
- Time: 4:05 PM EST
- TV: CBS
- Odds: Seahawks -2.5; Over/Under 44.5 (via FanDuel sportsbook)
Tennesse Titans (0-4) 4th AFC South @ Arizona Cardinals (2-2) 4th NFC West
- Location: State Farm Stadium, Glendale, Arizona
- Time: 4:05 PM EST
- TV: CBS
- Odds: Cardinals -8.5; Over/Under 41.5 (via FanDuel sportsbook)
Washington Commanders (2-2) 2nd NFC East @ Los Angeles Chargers (3-1) 1st AFC West
- Location: SoFi Stadium, Inglewood, California
- Time: 4:25 PM EST
- TV: FOX
- Odds: Chargers -2.5; Over/Under 47.5 (via FanDuel sportsbook)
Detroit Lions (3-1) 1st NFC North @ Cincinnati Bengals (2-2) 2nd AFC North
- Location: Paycor Stadium, Cincinnati, Ohio
- Time: 4:25 PM EST
- TV: FOX
- Odds: Lions -10.5; Over/Under 45.5 (via FanDuel sportsbook)
New England Patriots (2-2) 2nd AFC East @ Buffalo Bills (4-0) 1st AFC East
- Location: Highmark Stadium, Orchard Park, New York
- Time: 8:20 PM EST
- TV: NBC
- Odds: Bills -8.5; Over/Under 49.5 (via FanDuel sportsbook)
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