Week 4 of the 2025 NFL season will kickoff with a Thursday Night Football matchup between the Seattle Seahawks (2-1) and the Arizona Cardinals (2-1).
The Seahawks lead the all-time series between these teams, 29-22-1, and have won eight of their nine most-recent meetings. They last faced off in December 2024, with the Seahawks winning on the road in Arizona, 30-18.
There aren’t many former Eagles in Thursday’s matchup, but DE Josh Sweat is out there for the Cardinals defense, and CB Josh Jobe has been having a really good season for Seattle.
Here’s everything you need to know about tonight’s game.
Seattle Seahawks at Arizona Cardinals
TV Schedule
Game time: 8:15 PM EST
Channel: Prime Video
Date: Thursday, September 25, 2025
Location: State Farm Stadium | Glendale, AZ
Announcers: Al Michaels, Kirk Herbstreit, Kaylee Hartung (field reporter)
Radio: Westwood One
Online Streaming
Odds via FanDuel
Seattle Seahawks: -1.5 (-126)
Arizona Cardinals: +1.5 (+108)
Over/Under: 43.5
SB Nation Blogs
Seahawks: www.FieldGulls.com
Cardinals: www.RevengeoftheBirds.com
Open thread: Discuss Thursday night’s game in the comments below.
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