Thursday Night Football: Dolphins vs. Bills

Week 3 of the 2025 NFL season will kickoff with a Thursday Night Football matchup between the Miami Dolphins (0-2) and the Buffalo Bills (2-0).

The Dolphins lead the all-time series between these teams, 61-56-1, but the Bills have won 12 of the most recent 13 meetings. They last faced off back in November 2024, when the Bills won in Buffalo, 30-27. They’ve also faced off five times in the postseason, but the Bills have a 4-1 lead in that series, too.

Here’s everything you need to know about tonight’s game.

Miami Dolphins vs. Buffalo Bills

TV Schedule

Game time: 8:15 PM EST

Channel: Prime Video

Date: Thursday, September 18, 2025

Location: Highmark Stadium | Orchard Park, NY

Announcers: Al Michaels, Kirk Herbstreit, Kaylee Hartung (field reporter)

Radio: Westwood One

Online Streaming

FuboTV | Prime Video

Odds via FanDuel

Miami Dolphins: +11.5 (+610)

Buffalo Bills: -11.5 (-900)

Over/Under: 50.5

SB Nation Blogs

Dolphins: www.ThePhinsider.com

Bills: www.BuffaloRumblings.com

Open thread: Discuss Thursday night’s game in the comments below.

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