The New England Patriots (3-11) take a four-game losing streak into their contest with the New England Patriots (11-3) on Sunday, December 22, 2024 at Highmark Stadium. The Bills are heavy favorites in this one, with the spread posted at 14 points. The over/under in the contest is set at 46.5 points.

The Bills’ most recent contest was against the Detroit Lions, and they won by a score of 48-42.

Against the Lions, Josh Allen completed 23 of 34 attempts for 362 yards, with two touchdowns and no interceptions, for the Bills.

Last time out, the Patriots fell to the Arizona Cardinals, with 30-17 being the final score.

Bills vs Patriots betting information

NFL odds courtesy of BetMGM Sportsbook. Odds updated Saturday at 5:26 p.m. ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.

  • Spread Favorite: Buffalo (-14)
  • Moneyline: Buffalo (-1149), New England (+730)
  • Total: 46.5 points

Bills betting insights

  • Buffalo is 4-2 against the spread, and 6-0 overall, at home this year.
  • The Bills have covered the spread in a game nine times this season (9-5-0).
  • Buffalo has hit the over in all six home games this year.
  • This season, Bills games have hit the over 10 times.

Bills leaders

  • Allen: 3,395 PASS YDS / 242.5 YPG / 64.4% / 25 TD / 5 INT / 91 CAR / 484 RUSH YDS / 11 TD
  • James Cook: 171 CAR / 828 YDS / 63.7 YPG / 13 TD / 29 REC / 232 YDS / 17.8 YPG / 1 TD
  • Khalil Shakir: 71 REC / 774 YDS / 59.5 YPG / 4 TD
  • Amari Cooper: 40 REC / 481 YDS / 43.7 YPG / 3 TD
  • Keon Coleman: 23 REC / 481 YDS / 48.1 YPG / 3 TD

Bills vs Patriots game info

  • Date: Sunday, December 22, 2024
  • Time: 4:25 p.m. ET
  • City: Orchard Park, New York
  • Venue: Highmark Stadium
  • TV Channel: CBS
  • Live Stream: Fubo (Watch Bills vs Patriots on Fubo)
  • Live Stream: Watch on Paramount+

Watch the Buffalo Bills all season on Fubo!

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