Game-by-game predictions for every Bills game in 2024

Week 1: vs. Arizona Cardinals

Cardinals’ Josh Mauro (69) puts pressure on Bills’ Josh Allen (17) during the fourth quarter at State Farm Stadium in Glendale, Ariz. on Nov. 15, 2020.

Prediction: Win

Record: 1-0

The Cardinals have a lot to prove after a bad 2023… and an Orchard Park home opener is going to be difficult for anybody.

Week 2: at Miami Dolphins (Thursday)

Jan 7, 2024; Miami Gardens, Florida, USA; Buffalo Bills tight end Dalton Kincaid (86) is tackled by Miami Dolphins linebacker Jerome Baker (55) after running with the football during the second quarter at Hard Rock Stadium. Mandatory Credit: Sam Navarro-USA TODAY Sports

Prediction: Win

Record: 2-0

It’s a short week but still early on in the year so it’s less of a worry. What will be a worry is someone being a Dolphins fan here–Josh Allen seems to always save his best games for Miami.

Week 3: vs. Jacksonville Jaguars (Monday)

Oct 8, 2023; London United Kingdom, Buffalo Bills quarterback Josh Allen (17) carries the ball against Jacksonville Jaguars linebacker Josh Allen (41)during the first half of an NFL International Series game at Tottenham Hotspur Stadium. Mandatory Credit: Kirby Lee-USA TODAY Sports

Prediction: Win

Record: 3-0

The Bills get some revenge for losing to the Jaguars in London last year in a game where multiple players, such as linebacker Matt Milano, went down with injury.

Week 4: at Baltimore Ravens (Sunday night)

BALTIMORE, MARYLAND – OCTOBER 02: Lamar Jackson #8 of the Baltimore Ravens drops back to pass while being chased by Tremaine Edmunds #49 of the Buffalo Bills in the fourth quarter at M&T Bank Stadium on October 02, 2022 in Baltimore, Maryland. (Photo by Rob Carr/Getty Images)

Prediction: Loss

Record: 3-1

The Ravens are fresh off a visit to the AFC Championship. This is a tough road game.

Week 5: at Houston Texans

Oct 3, 2021; Orchard Park, New York, USA; Buffalo Bills tight end Dawson Knox (88) reacts to his touchdown catch and run as Houston Texans cornerback Terrance Mitchell (39) looks on during the first half at Highmark Stadium. Mandatory Credit: Rich Barnes-USA TODAY Sports

Prediction: Loss

Record: 3-2

Sorry to those upset at Stefon Diggs after he was traded to Houston… but the Texans look like a real powerhouse.

Week 6: at New York Jets (Monday)

Nov 19, 2023; Orchard Park, New York, USA; New York Jets cornerback D.J. Reed (4) tackles Buffalo Bills tight end Dalton Kincaid (86) after he made a catch during the first half at Highmark Stadium. Mandatory Credit: Gregory Fisher-USA TODAY Sports

Prediction: Loss

Record: 3-3

Assuming the Jets still have Aaron Rodgers under center by Week 6, it’s hard to win every single division game in a year.

Week 7: vs. Tennessee Titans

Buffalo Bills place kicker Tyler Bass (2) kicks a field goal during the second quarter against the Titans at Highmark Stadium Monday, Sept. 19, 2022, in Orchard Park, New York.

Prediction: Win

Record: 4-3

Back to winning ways. Not only are the Titans weakened on paper this season, the Bills would be motivated to bounce back.

Week 8: at Seattle Seahawks

Nov 8, 2020; Orchard Park, New York, USA; Buffalo Bills quarterback Josh Allen (17) passes the ball as Seattle Seahawks outside linebacker K.J. Wright (50) defends during the second quarter at Bills Stadium. Mandatory Credit: Rich Barnes-USA TODAY Sports

Prediction: Win

Record: 5-3

It’s a west coast trip so it will be difficult but the Bills can get the upper hand here.

Week 9: vs. Miami Dolphins

MIAMI GARDENS, FLORIDA – JANUARY 07: Khalil Shakir #10 of the Buffalo Bills is tackled by David Long Jr. #51 of the Miami Dolphins during the fourth quarter at Hard Rock Stadium on January 07, 2024 in Miami Gardens, Florida. (Photo by Megan Briggs/Getty Images)

Prediction: Loss

Record: 5-4

Again, it’s tough to win every game in the division and like it or not, the Dolphins are an improving team over the past few years. There’s a reason why Buffalo did not wrap up their fourth-straight AFC East title until the final week of the season last year.

Weeek 10: vs. Indianapolis Colts

Bills quarterback Josh Allen is brought down by Colts Ibraheim Campbell.

Prediction: Win

Record: 6-4

The Colts look like they might be rolling in the right direction. But by comparison, the Bills should edge them out at home if they’re serious.

Week 11: vs. Kansas City Chiefs

Jan 21, 2024; Orchard Park, New York, USA; Buffalo Bills quarterback Josh Allen (17) runs with the ball against the Kansas City Chiefs in the second half of the 2024 AFC divisional round game at Highmark Stadium. Mandatory Credit: Mark Konezny-USA TODAY Sports

Prediction: Win

Record: 7-4

The Bills have a better record against the Chiefs during the regular season than they do in the postseason. On top of struggling earlier on in the year during a tough stretch, Buffalo will want to win a big game in a big way here.

Week 12: Bye

ORCHARD PARK, NY – JULY 28: A general view of the helmets worn by Buffalo Bills players during training camp at the Adpro Sports Training Center on July 28, 2021 in Orchard Park, New York. (Photo by Timothy T Ludwig/Getty Images)

Prediction: Win (just kidding)

Record: 7-4

Week 13: vs. San Francisco 49ers (Sunday night)

Dec 7, 2020; Glendale, Arizona, USA; Buffalo Bills tight end Dawson Knox (88) is tackled by San Francisco 49ers cornerback Jason Verrett (22) during the third quarter at State Farm Stadium. Mandatory Credit: Michael Chow-Arizona Republic

Prediction: Win

Record: 8-5

The Bills will be well rested against a team traveling from across the country. The 49ers are a solid team, but another big win here for Buffalo.

Week 14: at Los Angeles Rams

Sep 8, 2022; Inglewood, California, USA; Los Angeles Rams wide receiver Ben Skowronek (18) runs the ball defended by Buffalo Bills cornerback Christian Benford (47) in the first quarter at SoFi Stadium. Mandatory Credit: Gary A. Vasquez-USA TODAY Sports

Prediction: Loss

Record: 8-5

The Rams have an attack on offense that might not bode well for the Bills and their retooling defense. This would be a letdown type of loss after beating the 49ers, but that happens.

Week 15: at Detroit Lions

DETROIT, MICHIGAN – NOVEMBER 24: Josh Allen #17 of the Buffalo Bills throws a pass against the Detroit Lions during the second half at Ford Field on November 24, 2022 in Detroit, Michigan. (Photo by Rey Del Rio/Getty Images)

Prediction: Loss

Record: 8-6

Week 16: vs. New England Patriots

Dec 31, 2023; Orchard Park, New York, USA; Buffalo Bills tight end Dalton Kincaid (86) makes a catch against the New England Patriots during the first half at Highmark Stadium. Mandatory Credit: Gregory Fisher-USA TODAY Sports

Prediction: Win

Record: 9-6

The Patriots are rebuilding and it’s hard to imagine them winning in Orchard Park at this time.

Week 17: vs. New York Jets

Nov 19, 2023; Orchard Park, New York, USA; Buffalo Bills wide receiver Khalil Shakir (10) runs for a touchdown after catching a pass as New York Jets safety Jordan Whitehead (3) pursues in the third quarter at Highmark Stadium. Mandatory Credit: Mark Konezny-USA TODAY Sports

Prediction: Win

Record: 10-6

In what could be a very contested game for playoff seeding, the Bills get some late-season revenge and potentially put a stranglehold on the AFC East again.

Week 18: at New England Patriots

ORCHARD PARK, NEW YORK – DECEMBER 31: Jordan Poyer #21 of the Buffalo Bills tackles Mike Gesicki #88 of the New England Patriots during the second half of the game at Highmark Stadium on December 31, 2023 in Orchard Park, New York. (Photo by Rich Barnes/Getty Images)

Prediction: Win

Record: 11-6

This is, of course, depending on if the Bills have anything to play for. It could be a loss if the seeding is locked in.